Fentanyl is an extremely powerful opioid painkiller that is 80 to 100 times stronger than morphine. It was approved by the U.S. Food and Drug Administration (FDA) for the treatment of late-stage breakthrough cancer pain in adults who are opioid tolerant or who have developed a tolerance for opioid medications as a result of long term treatment.
Cancer patients would definitely be familiar with some medications, like: Actiq, which is in lozenge form; Duragesic, which is in the form of a skin patch; Abstral, a sublingual tablet or a tablet that goes under the tongue; Fentora, a tablet that goes between the gum and cheek; and, Subsys, a sublingual spray.
Subsys, the most recent fentanyl-containing medication placed under legal spotlight, is manufactured, and was introduced in 2012, by drugmaker Insys Therapeutics, Inc. During the first half of 2015, this drug netted a $147.2 million profit for Insys, making it one of the biggest selling highly-addictive painkillers in the U.S. and around the world.
Use of Subsys, however, like all other fentanyl-containing drugs, poses great risk due to the possibility of abuse, misuse, addiction and overdose; using it on children can be fatal too. Due to the risks it presents, the FDA has Subsys mandated that it can only be prescribed (by healthcare professionals) and acquired (by patients) by enrolling in the Transmucosal Immediate-Release Fentanyl (TIRF) Risk Evaluation and Mitigation Strategy (REMS) Access program, a restricted program of the FDA.
It may be true that Subsys effectively and immediately controls breakthrough cancer pain; despite being effective, however, reports have surfaced which link this drug to about 203 deaths since it was introduced in 2012. This is besides the 52 Subsys-related deaths reported in the second quarter of 2015.
The risks, the deaths, plus allegations that Insys Therapeutics has illegally prescribed Subsys for off-label use (the major reason for the many cases of fatal overdose in individuals who are not suffering from cancer and, therefore, not opioid tolerant) has landed this drug in the “drugs of concern” list kept in the office of the U.S. Department of Health and Human Services’ Inspector General.
Patients who have been inappropriately prescribed with a powerful opioid medication, such as Subsys, can suffer serious and potentially fatal injuries, such as overdose. Seeking legal assistance from a highly-skilled Subsys spray attorney may be able to help the victim and/or his/her family pursue justice and the compensation he/she may be legally entitled to.
No matter how smooth flowing your plumbing system is, it is still bound to encounter some problems occasionally. While you can do some plumbing works yourself, there are times when letting the professionals handle such kind of jobs is the best option. According to the website of American Leak Detection of Dallas, some leaks are hidden that it will require an expert to locate them. So when is the best time to dial a plumber?
- When the main line has stopped
Repairing the main line of your plumbing system entails the use of special equipment which only plumbing companies have.
- When there are leaks in your walls, basements, or bathrooms
When water damage creeps in along your ceiling, walls, or floors, there might be a leaky interior pipe. These types of damage can lead to a more serious problem. So before it gets worse, call a plumber to locate, fix, or replace the leak.
- Your shower valve needs to be replaced
Choosing the right shower valve can be complex and time consuming if you do not have the experience. A professional plumber has the skill in changing the valve with minimal damage to your walls.
- Slow or Totally Clogged Drains
Slow or completely clogged drains can lead to serious problems. Attempting to find the cause of the problem yourself is a recipe for disaster. A plumber has the training, skill, and equipment for removing clogs without damaging your pipes.
Do-it-yourself plumbing can indeed save you plumbing repairs expenses. However, it can become a huge problem if you attempt to do the plumbing project yourself. By letting the professionals do their jobs, you can have some peace of mind when it comes to leaks and other plumbing-related issues. What’s a hundred bucks compared to having leak issues here and there.
As instituted by the Federal Motor Carrier Safety Administration (FMCSA), those who carry a commercial driver’s license (CDL) are held at a higher regard than those who have non-commercial driving licenses when it comes to driving under the influence. This is because regardless of what they are driving, commercial drivers present a serious danger to the safety of the public as well as become a major liability to their respective employers.
The majority of states in America has taken up the strict FMCSA regulations regarding alcohol levels for commercial drivers. Set at half the blood-alcohol concentration limit of non-commercial drivers, commercial drivers should have less than .04 percent BAC limit. Furthermore, those who have consumed alcohol are not allowed to drive a vehicle within 4 hours after they have consumed alcohol. This is to ensure that they will not be a risk on the road and prevent any road accidents.
The effects of being charged with commercial DUI can be extensive. According to Ausband & Dumont, aside from being subjected to the same procedures as non-commercial drivers, those who have been charged with commercial DUI can face a lengthy license suspension. This could lead to loss of employment and financial struggles for the driven and their family. Additionally, those who have been convicted of DUI (regardless of whether he was on duty or not at that time) has to inform their employer about the court’s decision and their license suspension or revocation. The employer should prevent the CDL-driver from operating until the end of their license restriction. This often makes re-employment very difficult for the driver because the DUI conviction is already on their records.
There are many ways with which a commercial driver will be required to take a random alcohol test, such as a when there is viable suspicion, after an accident, or as part of the requirements to return from work after a suspension. FMCSA additionally requires drug testing as part of a condition for employment, after an accident, when there is feasible suspicion, and as a prerequisite to go back to work. Refusing to submit to any of these tests can lead to a more severe penalty, and could lead to a guilty plead for DUI according to FMCSA rules.
After the initial Volkswagen scandal discovery of millions of cars outfitted with software to avoid strict emissions regulations, the chief executive of the German auto manufacturer Martin Winterkorn resigned. His replacement was announced on September 25 as head of Porsche, Matthias Muller. Along with the announcement of the new chief executive came companywide changes that are intended to repair damage to the company after “Dieselgate.”
The effects of the Volkswagen software that duped emissions tests on the diesel models is yet undetermined. The environmental impact is considered to be substantial with 11 million vehicles around the world emitting nitrogen oxides 10 to 40 times above U.S. legal limits, according to the the website of the Driscoll Firm. This was done by the “defeat device” inserted into diesel passenger cars that sense when a vehicle is being tested rather than driven on a road, triggering the vehicle emissions to regulation levels.
Berthold Huber, the chairman of the company’s supervisory board called the incident “a moral and political disaster.” Under the new chief executive, removal of several leaders in connection to the scandal is underway. Among the suspended individuals is Christian Klingler, the former top sales and marketing executive at Volkswagen. As stock and sales continue to drop around the globe, Volkswagen hopes that the new leadership will promote the regrowth of trust.
One of the main concerns for consumers is in regards to compensation that that former Chief Executive Martin Winterkorn promised was coming. Volkswagen made a statement assuring that $7.3 billion dollars was set aside for VW diesel passenger vehicle owners affected by the scandal. In the wake of falling estimated values of affected vehicles, many drivers are upset that they were deceived into harming the environment and are now possess fraudulent vehicles. However no plan has been released to the public on how these funds will be distributed to the car owners. However no plan has been released to the public on how funds will be distributed to the car owners.
Many of the regular dog food brands you will find in the supermarket are much cheaper than the all natural dog food varieties available. This is mainly because regular dog foods are often made up of a lot of fillers and food scraps from meat, poultry and produce processing plants that would otherwise be thrown out. It can be tempting to go for price rather than quality, but it may cost you more in the end. Here are 5 benefits you can get from an all natural dog food diet.
An all natural food diet especially formulated for dogs takes into consideration the needs of your pet. Dogs are not people, and there are some foods that they simply cannot digest. Grains such as wheat, corn and soy found in regular dog food acts as a stopper, keeping essential nutrients from being absorbed by the body. The dog becomes lethargic and obese and may even develop digestive problems.
Healthier coat and skin
Dogs can develop allergies to artificial preservatives, flavors and colors used in regular dog food. It manifests in skin rashes, excessive shedding and digestive upsets. All natural dog food formulas by definition do not include these ingredients.
Fewer trips to the veterinarian
When a dog gets the right kind of nutrition, there is no reason why a visit to the veterinarian is necessary save for an annual check-up, immunization shots and the like. A healthy dog saves you money on vet visits, medical procedures and medications.
No need for supplements
Most of the good-quality all natural dog food brands incorporate the essential vitamins and minerals needed by dogs as recommended by the Association of American Feed Control Officials (AAFCO). If you buy the right dog food for your dog’s particular breed, size and age and follow the feeding guidelines, then you will not have to buy supplements separately.
Happier pet and pet owner
Good quality all natural dog food is more expensive but the savings from having a healthy dog all the time will more than make up for your investment. Moreover, healthy dogs are generally happy, well-adjusted and alert, and that makes pet owners happy as well.
According to The Rugged Pup, for best results you should gradually acclimate your dog if you are switching to an all natural dog food diet. This will ensure that the transition is smooth and mess-free, and prevent intestinal distress.
The permeation of polychlorinated biphenyls or PCBs is nothing short of epic. Because it was used in so many products, it has gotten into everything directly or indirectly. It is a real challenge to recycle even paper without tripping on legal statutes.
The laws that apply to toxic Monsanto PCBs (Monsanto Company was the only PCB producer in North America back in the day) are mainly the Toxic Substances Control Act of 1976 (TSCA) and the Clean Water Act of 1972 (CWA). Both laws pertain to the amount that a toxic substance can be present in any substance.
In the case of old newspapers, recyclers find themselves in what is called the PCB paradox. The ink in these old newspapers contains PCBs among other harmful substances. The TSCA allows ink producers to use PCBs as a stabilizer as long as it is not more than 50 parts for million. What recyclers do is remove the ink and treat the PCBs, but still a little bit remains in the wastewater, which usually goes into the river or the sewage plant. At this point, the CWA regulations kick in, which prohibits wastewater with more than 64 parts per quadrillion of PCBs. That is about 700 million times less than what legally goes into the plant in the form of newspaper ink.
This is a decided blow on the recycling movement, because these federal regulations make this impossible on an industrial scale. However, it is important to remember that the small amounts of PCBs discharged into the environment at this point would not have been such a big deal if Monsanto had not already recklessly discharged thousands of pounds of PCB-laden effluent. As it is toxic Monsanto PCBs are everywhere and in everything at dangerous levels. The laws are simply trying to achieve a balance between industrial need and environmental protection. If anyone should be blamed for the PCB paradox, it is the PCB producer.
Spending time in Appleton, Wisconsin? No one can blame you as it has been reported to be one of the best places to live in the United States of America. There are plenty of facilities where you and your family can enjoy your stay in Appleton and truly experience the very best that this town has to offer.
Thinking of a place where your kids can have the most fun? The Building For Kids could be exactly what you’re looking for. Spacious enough to contain a lot of educational and exciting exhibits for kids, as well as crafting areas where children are encouraged to expand their horizons and express with their imaginations, it is the perfect space for kids and parents to spend time with each other while learning new things as well!
Another quite picturesque space where the family can spend time are the Butterfly Gardens of Wisconsin. Truly beautiful and magnificent to behold, it’s like stepping into the gardens that only fairytales told you about when you were little – or the ones that your little ones still believe in. Surrounds yourself with nature and all the delicate beauty it has to offer, these gardens allow for you and your family to rekindle your soul with nature, which is always healthy. These are also quite educational for the children as they can learn about different species and appreciate nature and its many splendors firsthand.
But, truly, if you’re going to Appleton, Wisconsin – a trip to The History Museum at the Castle is mandatory in order to get the full Appleton experience. What a waste it would be if you were not to take advantage of this incredible opportunity to see all of Appleton’s wonderful history, complete with exhibits that detail the lives of notable people from this town such as Harry Houdini and Edna Ferber. There is something in this museum for everyone – kids and adults alike – and so it would really be recommended if you’re going to stop by and spend some time in Appleton, Wisconsin.
“Do not pity the dead, Harry. Pity the living.” These are words spoken by Albus Dumbledore in the famed story that is known to nearly every living person in the world today. Unfortunately, these are words that are more than simple musings of a fictional character – these are words that hold a harsh truth for it is the living who must then deal with the repercussions of having to live without their deceased loved ones.
Losing a beloved is never easy and the life lost cannot be replaced by any sum of money or with any goods or apologies. According to the law offices of Hankey Law Office P.C., if liability can be determined to an offending guilty party, showing proof that the death was born out of negligence by that given individual or corporation, then there is unrest where peace should only reign. It can be exceedingly difficult to deal with the aftermath of loss as these are trying, emotionally charged times that can muddle the legal proceedings that can be quite perfunctory and tedious. This is why starting your claim as soon as an incident occurs is vital to quickly receiving compensation.
If prior the to death, the victim suffered wounds or damage that required medical attention, the surviving beneficiaries of the victim is entitled to reimbursements for the procedures, as well as compensation for the loss of income that befalls the loved ones now left behind and in what can only be an extremely difficult situation. Financial recompense will never replace the love and company now lost to you forever but there is some small measure of comfort that can allow you to transition back into some kind of normal in as smooth and efficient a manner as possible.
If you or someone you know has suffered a similar circumstance, do look into availing the services of a wrongful death attorney who can help you make things right. With the right kind of help, you need not even doubt the possibility that in the years now to come, even after the pain of this loss has come upon you, all can be well again.
Every year the US Department of Transportation’s National Highway Traffic Safety Administration (NHTSA) receives reports of about 10,000 deaths and, at least, 24,000 cases of serious injuries due to rollover accidents involving, most especially, SUVs. Next to head-on collision accidents, rollovers register the highest number of deaths and grave injuries.
Any type of vehicle can rollover, most especially those that have worn out tires as the vehicle can easily lose traction and those that have the tendency to understeer, or turn lesser that intended, or oversteer, that is turn farther than it was meant to. However, because SUVs are designed with a higher center of gravity from the ground, this makes them more prone to rollover accidents than ordinary cars.
The law firm of Williams Kherkher explains on its website how a serious accident can dramatically change a victim’s (and his/her family’s) present and future life/lives, especially if the physical injury and trauma leads to disability that will render the victim incapable of reporting to work for weeks or months; besides the loss of the capability to earn the victim can be faced with costly medical treatment, which he/she cannot but choose to undergo to help him/her recover.
One modern safety device that manufacturers of cars have found that could significantly lower occurrences of rollover accidents is the Electronic Stability Control (ESC). This safety feature, which the NHTSA has directed vehicle manufacturers to incorporate in their brand new and future cars, consists of sensors that have been enabled to detect loss of vehicle control. As loss of control is detected, the device applies brakes on the appropriate wheel automatically to allow the driver regain and maintain control and put the vehicle back on track. ESC is also able to help stabilize the vehicle during abrupt turns, eliminate chances of oversteering and understeering, improve traction on slippery or icy roads, and improves vehicle control on road shoulders and gravel patches.
Designing an SUV with a higher center of gravity that makes it more likely to rollover may be considered a failure in design by the manufacturer. And this act of negligence, if it ends in a personal injury, can put the manufacturer in a situation wherein he/she would be held legally responsible for any injury sustained and probably be required to compensate the victim for all present and future damages.
Consulting with a Houston personal injury lawyer, who is highly-competent in the field of tort law, can give the victim all the legal help that he/she needs and may be even be awarded by the court the full amount of compensation allowed by the law.
The axe has fallen. Johnson & Johnson (J&J) has been named as a defendant in US District Court for the Eastern District of California for its baby powder line of products. The plaintiff, Mona Estrada, alleges in her filing on April 28, 2014 that J&J did not include a warning about the increased risk of ovarian cancer with the genital use of talcum powder in their labels despite studies indicating that there is a link. The talcum powder lawsuit lawyers at Williams Kherkher cite on their website a Science World Report statement that the risk of women developing ovarian cancer is increased by 24% with the genital use of talcum powder.
Previous to this, a jury in South Dakota federal court had found for plaintiff Deane Berg of Sioux Falls, who had filed suit in 2009 after discovering that the talcum powder she had used for 30 years may have caused the ovarian cancer diagnosed in 2006. The jury agreed that J&J had failed to warn consumers about the risks associated with genital use of talc-based products. However, the jury did not believe that the product was defective and did not award damages. J&J filed a “motion for judgment as a matter of law” but U.S. District Judge Karen Schreier upheld the jury verdict; an award was still not given. Under South Dakota law, a finding of liability may still include an award of zero. Berg filed a motion for a new trial challenging the award portion of the ruling in April 2014, which was denied.
The value of this first lawsuit is that it established a precedent for this type of case, and can pave the way for other plaintiffs, whether individually or as a group, to bring issue with J&J over its negligence by failing to warn consumers about the potential danger. Records show that J&J had known about the link between their products and ovarian cancer since 1982. The author of a study indicating this was contacted about it by a J&J representation and recommended that a warning label should be added.
A putative class action is not a true class action suit until it is certified by a judge as such. If you have developed ovarian cancer that may have been caused by using Johnson’s baby powder or related product, contact a reputable talcum powder lawyer in your area to see if you can file a personal injury lawsuit against J&J.